IFN alpha

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Information
Drug Name
IFN alpha
Description
Entry(CIViC)
CIViC
[No Data.]
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
Uveal melanoma. In a non randomized trial, low dos... IFNAR1 IFNAR1 UNKNOWN Resitance or Non-Reponse true MMMP detail
IFN alpha-induced p-STAT1 correlated with the anti... STAT1 STAT1 UNKNOWN Sensitivity true MMMP detail
Reexpressing DR4 by 5-AZAdC in melanoma cells in w... TNFRSF10A TNFRSF10A OVEREXPRESSION Sensitivity true MMMP detail
Pretreatment of 1205Lu cells with MEK1 inhibitor P... MAP2K1 MAP2K1 UNDEREXPRESSION Sensitivity true MMMP detail
Activation of IFNAR and TLR3 shows synergistic the... TLR3 TLR3 OVEREXPRESSION Sensitivity true MMMP detail
Uveal melanoma. The ATP chemosensitivity assay was... MYC MYC EXPRESSION Resitance or Non-Reponse true MMMP detail
Inhibition of DNMT1 seems to act through demethyla... DNMT1 DNMT1 UNDEREXPRESSION Sensitivity true MMMP detail
SOCS3 inhibition seems to act through STAT1 activa... SOCS3 SOCS3 UNDEREXPRESSION Resitance or Non-Reponse true MMMP detail
Significantly increased overall and disease free s... IFNAR1 IFNAR1 UNKNOWN Sensitivity true MMMP detail